Makamba had a high profile as a broadcaster and had come from a wealthy family.
He was diagnosed with coronavirus on Saturday, and his condition deteriorated rapidly after he was admitted to an isolation centre in the capital, Harare.
Meanwhile, the first man to contract the virus is said to be recovering well in self-isolation.
There are concerns about Zimbabwe’s ability to cope with the disease, even if there are only a few cases. A nation which, at the best of times, has shortages of basics such as painkillers, gloves and masks, and a more critical shortage of ventilators and oxygen tanks.
As reality sinks in, Zimbabweans have begun observing a ban on large gatherings.